I've been using MIT45 Super K for a little over a year now for pain relief from damaged knees and inflammation from my Lupus as I'm unable to anti-inflammatories. The taste is awful, not gonna lie, lol, but I follow with a few swigs of OJ and within about 20 minutes my pain starts to settle. I use it daily, once or twice depending on how bad my flares are hitting me. I keep my doses on the small side so as not to build up a tolerance and every couple weeks I taper it back for a day or so for the same reason and it works best that way. With this bottle you get the most for your money and can stretch it out into multiple doses. Definitely satisfied with the product and thankful to have a product to help with pain control when the Dr's are either unable or unwilling to do anything for you.